1.
Respir Med
; 187: 106597, 2021 10.
Article
in English
| MEDLINE | ID: covidwho-1377827
ABSTRACT
Based on computerized modeling studies, it has been postulated that the severe hypoxemia in COVID-19 may result from impaired oxygen carrying capacity on hemoglobin. Standard pulse oximetry may not detect hypoxemia resulting from hemoglobinopathy, therefore hemoglobin co-oximetry is needed to evaluate this divergence. In a clinical data analysis of a multicenter cohort of hospitalized patients with COVID-19, we found a minimal effect, less than 1%, on the correlation between oxyhemoglobin concentration and predicted oxygen saturation in the presence of COVID-19 infection. This effect is unlikely to explain the clinically significant hypoxia in COVID-19 patients.
Subject(s)
COVID-19 , Hemoglobinopathies , Humans , Hypoxia , Oximetry , Oxygen , Oxyhemoglobins/analysis , SARS-CoV-2
2.
JAMA Intern Med
; 180(11): 1537-1539, 2020 11 01.
Article
in English
| MEDLINE | ID: covidwho-609243